Santa Ana South of First (69) Homes with Mixed Use Subtype

Welcome to Santa Ana South of First (69), a vibrant and eclectic neighborhood nestled in the heart of Orange County, California. Known for its rich cultural tapestry and dynamic community spirit, this area offers a unique blend of residential charm and commercial opportunity, making it an ideal place for both homeowners and entrepreneurs.

The South of First district is characterized by its historic architecture, artistic flair, and a burgeoning lifestyle scene. Residents enjoy a variety of local amenities, including trendy cafes, boutique shops, and cultural hotspots that celebrate the area's diverse heritage. The neighborhood is also conveniently located near major transportation routes, providing easy access to the rest of Orange County and beyond.

One of the standout features of this region is its mixed-use homes, which allow for a seamless integration of living and working spaces. These properties are perfect for those who seek a live-work lifestyle, offering the flexibility to run a business from the comfort of home while enjoying the benefits of neighborhood camaraderie. With a range of architectural styles and sizes, you can find a mixed-use home that perfectly fits your vision, whether it’s a chic loft or a charming bungalow.

Santa Ana South of First is not just a place to live; it's a community where creativity thrives, and possibilities abound. Whether you’re an artist, a small business owner, or simply someone looking to embrace a vibrant urban lifestyle, this neighborhood offers the perfect backdrop for your next chapter. Explore the charm and opportunity that awaits you in Santa Ana South of First!

Newest Santa Ana South of First (69) Homes with Mixed Use Subtype

$899,999

IV26154060 MLS ⋅ Active Status

This multi-use building in the City of Santa Ana offers endless potential for business owners ready to grow, developers looking for their next project, or investors seeking long-term value. Whether you envision retail, office, or a mixed-use concept, this property is a blank canvas in a thriving market.

1902 S Standard, Santa Ana

$4,500,000

PW26133426 MLS ⋅ Active Status

505 S Main Street presents a rare opportunity to acquire a high-visibility commercial asset positioned on a commanding hard corner in central Santa Ana. Boasting outstanding frontage on three separate streets including a major signalized intersection along South Main Street this premium corner lot spans approximately 0.90 acres (39,640 SF) and handles a heavy daily traffic volume exceeding 28,000 vehicles per day. The existing structure features a substantial ±18,650 square foot commercial footprint (comprising massive ground-floor showroom/warehouse space plus a functional second-story open workspace and private office layout). Supported by 44 gated, on-site parking spaces, the property provides immediate utility for an owner-user or retail repositioning. Beyond its current footprint, the property holds massive value-add potential. Designated under the city's favorable UN-20 (Urban Neighborhood) zoning framework, the site supports up to 20 dwelling units per acre and a 1.0 Floor Area Ratio (FAR). This highly versatile zoning enables a wide array of adaptive reuse strategies, including vertical mixed-use, live/work spaces, or an intensive residential infill redevelopment. Located just blocks from the booming Downtown core, the Civic Center, and direct transit lines, this asset is perfectly positioned to capture the immense public and private capital transforming the urban core of Santa Ana.

505 S Main, Santa Ana

$1,179,000

PW26136122 MLS ⋅ Active Status

Excellent investment opportunity in Santa Ana! This income-producing triplex offers three separate units on a large lot with ample parking and strong rental potential. Unit A, the front downstairs unit, features a spacious 1-bedroom, 1-bath floor plan. Unit B, located upstairs, offers 2 bedrooms and 1 bathroom. Unit C, the rear unit, also features 2 bedrooms and 1 bathroom. Each unit is separately metered for gas and electricity, providing convenience for both owners and tenants. Units B and C each include an enclosed garage. The property is currently tenant-occupied, generating monthly rental income. Situated on a generous lot, this property is within walking distance to parks, schools, churches, shopping, restaurants, and other local amenities. Conveniently located near the 55 and 405 freeways, this is an excellent opportunity for investors seeking steady cash flow or owner-occupants looking to live in one unit while generating rental income from the others. Don't miss this chance to own a versatile multi-unit property in a desirable Santa Ana location.

608 E Central Avenue, Santa Ana

$774,900

OC26051319 MLS ⋅ Active Status

Excellent Opportunity to own a Commercial building in the heart of Henninger Park in Historic Santa Ana along the well trafficked South Broadway corridor. This property boasts 3 units, each with their own electric meter, and a nearly 5:1 parking ratio with a fully enclosed and gated parking lot with up to 15 gated parking spaces and plenty of off-street parking as well. Each unit has its own private bathroom. Bonus full sized basement allows for additional storage and access to all plumbing and electric for service, maintenance and repairs. There is huge upside in rents with all the current tenants on month-to-month leases well below market value. This property has very unique zoning (SD-40) which allows for either residential or a variety professional and retail commercial uses. Convert this property to residential units and really hit an income home-run with at least $6,000/month of pro forma gross income. Roof was replaced in 2017, all new ABS plumbing waste-lines in 2018, all copper plumbing throughout and a mini-split heat pump (HVAC) in unit 624 in 2018. Parking lot was completely repaved and striped in 2025. This one won't last long, so come quick!

626 S Broadway, Santa Ana

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Based on information from California Regional Multiple Listing Service, Inc. as of . This information is for your personal, non-commercial use and may not be used for any purpose other than to identify prospective properties you may be interested in purchasing. Display of MLS data is usually deemed reliable but is NOT guaranteed accurate by the MLS. Buyers are responsible for verifying the accuracy of all information and should investigate the data themselves or retain appropriate professionals. Information from sources other than the Listing Agent may have been included in the MLS data. Unless otherwise specified in writing, Broker/Agent has not and will not verify any information obtained from other sources. The Broker/Agent providing the information contained herein may or may not have been the Listing and/or Selling Agent.